在使用生物阻抗光谱学评估下肢淋巴时,身体定位的影响
Louise A Koelmeyer1, Katrina Gaitatzis1, Belinda Thompson1
1Australian Lymphoedema Education, Research and Treatment Centre, Department of Health Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Lymphatic research and biology
|October 18, 2023
概括
腿部淋巴瘤的生物阻抗光谱 (BIS) 测量在各种位置和设备上都是可靠的. 然而,数据是不可互换的,需要设备和位置特定的参考范围来获得准确的L-Dex分数.
科学领域:
- 生物医学工程 生物医学工程
- 临床诊断 临床诊断 临床诊断
- 淋巴 edem 研究 研究 淋巴 edem 研究
背景情况:
- 生物阻抗光谱 (BIS) 对于评估流体状况和诊断淋巴等疾病至关重要.
- 传统的BIS使用卧式定位与凝支持的电极,而新的站立式设备使用固定电极.
- 测量位置和设备类型的变化可能会影响BIS的准确性和可比性.
研究的目的:
- 为了比较使用和站立设备的BIS测量,躺卧,坐着和站立.
- 评估这些测量的可靠性和一致性,在有或没有单边腿淋巴的人群中.
- 评估位置和设备对L-Dex分数分类的影响.
主要方法:
- 横截面研究涉及24名患有单边腿淋巴的参与者和71名健康对照人.
- 三次BIS测量是在卧卧,坐着和站着的位置使用和站立装置进行的.
- 阻抗值和L-Dex分数分析了可靠性,设备和位置之间的差异以及分类准确性.
主要成果:
- 这两种设备在所有位置都显示出可靠的阻抗测量 (CV ≤ 0.6%).
- 设备之间的平均阻抗差异在1%至6%之间.
- L-Dex评分显示了设备之间的高相关性 (r=0.82), ~70%的淋巴分类协议;然而,在对照中,随着站立设备出现了显著的腿间差异.
结论:
- 可靠的腿阻抗测量可以在躺着,坐着或站着的两种BIS设备中实现.
- 不建议在主导和自动BIS设备之间直接交换数据.
- 使用设备和位置特定的参考范围对于准确的L-Dex评分解释至关重要,以最大限度地降低错误分类风险.
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