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Updated: Jul 13, 2025

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调控性T细胞特异性淘汰Notch2的长期后果在免疫平衡中

Hui-Ming Fan1, Yue-Long Qiao1, Yan Liu2

  • 1Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, 238 Jie-Fang Road, Wuhan, Hubei 430060, PR China.

International immunopharmacology
|October 18, 2023
PubMed
概括

在调节性T (Treg) 细胞中淘汰Notch2会损害它们的功能和数量,导致自发炎症. 在Notch2KO小鼠中,这种免疫失衡随着年龄的增长而恶化.

关键词:
CD4+ T 细胞子集 CD4+ T 细胞子集免疫系统的平衡.标记2 标记2 是一个标记.监管T细胞监管T细胞

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