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Updated: Jul 13, 2025

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未经编辑的异构iNKT细胞在MHC不匹配的狗接受者中显示出长时间的持久性

Antonia Rotolo1, Eoin C Whelan2, Matthew J Atherton3

  • 1Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Cell reports. Medicine
|October 18, 2023
PubMed
概括

研究人员确定了生物标志物,以改善癌症和COVID-19治疗的全基不变天然杀手T细胞 (allo-iNKTs) 的持久性. 这一策略提高了 allo-iNKT 的存活率,而不需要广泛的预先条件,提供了一个通用的细胞治疗平台.

关键词:
全基因不变的自然杀手T T生物标志物 生物标志物狗类模型 狗类模型供体选择 供体选择捐赠者-接受者MHC不匹配情况现成的采用细胞疗法

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