患有多发性硬化症的儿童和青少年的听觉中心通路
Dayane Aparecida Nascimento Barbosa1, Liliane Aparecida Fagundes Silva1, Alessandra Giannella Samelli1
1Universidade de São Paulo, Faculdade de Medicina, Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional, São Paulo SP, Brazil.
Arquivos de neuro-psiquiatria
|October 18, 2023
概括
患有多发性硬化症 (MS) 的儿童和青少年表现出异常的听觉唤起潜能,表明神经传导延迟和处理缺陷. 这些发现突显了MS对年轻人的中央听觉通路的影响.
科学领域:
- 神经科学是一个神经科学.
- 儿科 儿科 儿科
- 听力学 听力学是指听力学.
背景情况:
- 多发性硬化症 (MS) 是一种影响中枢神经系统的炎症性脱髓化疾病.
- 听觉唤起的潜在研究表明,成年人患有多发性硬化症的神经处理缺陷.
- 儿科多发性硬化症患者的电生理学反应仍未得到充分研究.
研究的目的:
- 评估患有多发性硬化症的儿童和青少年的中央听觉通路.
- 利用大脑干听觉唤起的潜能 (BAEP) 和长延迟听觉唤起的潜能 (LLAEP).
主要方法:
- 该研究包括17名儿科多发性硬化症患者 (9-18岁) 和17名健康对照.
- 所有参与者听力正常,没有中耳问题.
- 使用点击-BAEP和LLAEP进行评估,并使用奇怪的范式和音频爆发刺激.
主要成果:
- 在60%的MS患者中发现了异常的电生理学反应.
- 在MS患者中,BAEP显示波V延迟延迟和延长的间峰延迟 (III-V,I-V).
- 在52.94%的MS患者中,LLAEP显示出异常反应,通常有更长的延迟时间和更小的幅度.
结论:
- 儿科MS患者表现出异常的BAEP,表明神经传导延迟.
- 异常的LLAEP结果表明神经处理速度降低和听觉感官歧视.
- 这些发现强调了MS年轻人的听觉通路功能障碍.
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