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Updated: Jul 13, 2025

Automated Dissection Protocol for Tumor Enrichment in Low Tumor Content Tissues

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Published on: March 29, 2021

对大型内镜下粘膜切割 (ESD) 标本的两种病理处理方法的比较.

Zixiang Yu¹, Dongxian Jiang¹, Wen Huang¹

¹Department of Pathology, Zhongshan Hospital Fudan University, Shanghai, China.

Journal of clinical pathology

|October 18, 2023

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处理大型内镜下膜剖析 (ESD) 标本的新方法显著减少了对块,储存空间和病理评估时间. 这种优化的技术提高了组织病理学评估的效率和准确性.

科学领域:

胃肠病学胃肠病学
病理学病理学病理学
手术瘤学手术瘤学

背景情况:

对内镜下粘膜切割 (ESD) 标本进行准确的基因病理评估对于患者管理至关重要.
大型ESD标本 (≥4厘米) 存在处理挑战.

研究的目的:

引入和评估用于大结直肠ESD标本的新型处理技术.
在区块数,存储和时间方面评估优化方法的有效性.

主要方法:

一项涉及92名结直肠瘤患者的比较研究,他们接受了ESD治疗.
使用常规方法处理的46个标本和使用优化技术使用的46个标本使用了宏观卡塞特和L形嵌入模具.

主要成果:

优化的方法显著减少了对块的数量 (276比398) 和总储存容量 (4554.0厘米3比6208.8厘米3).
通过优化技术,病理评估时间大大缩短了 (164.5分 vs. 269.0分).

结论:

针对大型ESD标本的优化技术有效地减少了工作量和存储需求.
这种改进的程序促进了准确的组织病理学评估,有助于临床决策.

关键词:

结直肠瘤是什么意思诊断诊断诊断诊断诊断诊断病理学,外科手术.

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