在全身性红血性狼中,患者共同支付和药物坚持的相关性
Raisa Lomanto Silva1, Gretchen M Swabe2, Sebastian Eduardo Sattui2
1Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Lupus science & medicine
|October 18, 2023
概括
高额的药物联合支付显著降低了系统性红斑狼 (SLE) 患者的治疗坚持. 降低患者的成本共享对于改善对基本SLE治疗的坚持至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 卫生经济学 卫生经济学
- 药学流行病学 药学流行病学
背景情况:
- 系统性红斑狼 (SLE) 需要长期使用氧化和免疫抑制剂等药物进行治疗.
- 药物坚持对于管理SLE和预防疾病爆发至关重要.
- 患者自付的费用,特别是共同支付,可能会影响患者的治疗坚持.
研究的目的:
- 检查SLE患者的药物共同支付水平和治疗坚持之间的关联.
- 为了确定氧化和特定免疫抑制剂的更高的付费是否与较低的坚持率相关.
主要方法:
- 从Optum的Clinformatics Data Mart数据库 (2010-2019) 中对非识别健康声明数据的回顾性分析.
- 纳入标准:患有SLE的个人和连续入学180天.
- 合规性定义为覆盖日数≥80%的比例;共付费分为高 (≥10美元) 或低 (<10美元) 的30天供应.
主要成果:
- 分析包括12510名SLE患者; 76%接受氧化,15%接受氧化加免疫抑制剂.
- 高额支付与降低对氧化 (OR 0.61),阿扎西奥普林 (OR 0.44) 和甲酸 (OR 0.69) 的坚持有显著的关联.
- 在高额共同支付和坚持甲状腺素治疗之间没有发现显著的关联.
结论:
- 较高的药物共同支付与减少对关键SLE治疗的坚持有关.
- 医疗保健策略应考虑共同支付对患者执法效率的影响.
- 通过较低的共同支付来减少财务负担,可能会改善药物坚持和SLE管理.
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