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Updated: Jul 13, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants

Published on: June 6, 2025

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MYC乙化氨酸残留物驱动瘤细胞转化,并调节选择的遗传程序,以实现细胞粘附独立的生长和存活

Matthew Hurd1, Jeffrey Pino1, Kay Jang1

  • 1Department of Biochemistry, University of California Riverside, Riverside, California 92521, USA.

Genes & development
|October 18, 2023
PubMed
概括

通过p300和GCN5的MYC乙化是可逆的,并影响MYC蛋白的稳定性和功能. 特定的乙化素 (AcK) 位点对于MYC驱动的癌细胞转化和瘤发生至关重要.

关键词:
在MYC上,MYC是蛋白.溶氨酸乙化溶氨酸恶性转变的恶性转变

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