肥胖成年人的肺和胸壁功能
Antonella Lo Mauro1, Gabriella Tringali2, Franco Codecasa3
1Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Piazza L. Da Vinci, 20133, Milan, Italy. antonella.lomauro@polimi.it.
Scientific reports
|October 18, 2023
概括
肥胖严重影响呼吸,导致胸部限制和增加通风,即使在其他健康个体. 光电子胸膜扫描揭示了肥胖症.
科学领域:
- 肺部医学 肺部医学
- 肥胖问题研究研究
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 肥胖通常与呼吸系统疾病有关.
- 了解严重肥胖对呼吸机制的影响至关重要.
研究的目的:
- 研究极度肥胖如何影响呼吸功能.
- 为了确定与肥胖相关的特定呼吸模式.
主要方法:
- 对比了17名肥胖者 (BMI 39.7 kg/m2) 与10名正常加重的对照.
- 使用光电子囊造影 (OEP) 进行胸腔腹部分析.
- 评估了躺卧姿势下静止时的呼吸模式.
主要成果:
- 肥胖患者的腹部体积更大 (41%与31%) 和更高的每分钟通风率 (11.9 L/min与7.5 L/min).
- 肥胖个体显示胸腔贡献减少 (5.7%与31.1%相比),表明胸部限制.
- 17%的肥胖患者出现了限制性肺部缺陷;OEP局部化了这种限制.
结论:
- 严重的肥胖会导致胸部限制和改变呼吸模式,即使没有系统的限制性肺部缺陷.
- 光电子胸膜扫描为与肥胖相关的呼吸机制提供了宝贵的见解.
- 肥胖对呼吸的影响是局部的,可以通过OEP测量.
相关概念视频
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
2.8K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
2.8K
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.8K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.8K
Chronic Obstructive Pulmonary Disease
1.3K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.3K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
Factors Affecting Pulmonary Ventilation
1.4K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
1.4K
Physical Assessment of the Respiratory Tract II: Inspection
310
Physical assessment of the respiratory tract through inspection is a crucial step in understanding the patient's respiratory health. It provides insights into the functioning of the respiratory system, the musculoskeletal structure, and even the patient's nutritional status. This comprehensive approach involves observing several vital aspects: chest configuration, breathing patterns, respiratory rates, skin color, and use of accessory muscles.
Chest Configuration
The chest configuration...
Chest Configuration
The chest configuration...
310


