一次性面罩废物燃烧会产生神经活性烟雾颗粒物
Artem Pastukhov1, Konstantin Paliienko2, Natalia Pozdnyakova1
1Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, 9 Leontovicha Str, Kyiv, 01054, Ukraine.
Scientific reports
|October 18, 2023
概括
燃烧一次性医疗口罩会释放神经毒性超细颗粒,影响神经递质平衡和神经元功能. 这种塑料污染有助于环境污染和潜在的神经病理学.
科学领域:
- 环境科学 环境科学
- 神经科学是一个神经科学.
- 材料科学 材料科学 材料科学
背景情况:
- 由于COVID-19的流行,大量的一次性医疗面具废弃物产生.
- 在全球范围内,面罩对于预防空气传播感染至关重要.
- 目前的废物管理实践不足以应对这种日益增长的塑料污染.
研究的目的:
- 为了研究由燃烧一次性医疗面罩产生的颗粒物的神经毒性潜力.
- 为了描述面罩烟雾的物理化学特性.
- 评估这种颗粒物对神经元功能和神经递质系统的影响.
主要方法:
- 从燃烧的聚烯面罩中收集和描述烟雾颗粒物.
- 分析颗粒大小,泽塔潜力,表面群和光学特性.
- 在孤立的老鼠皮层神经终端上进行的神经化学研究,测量神经递质的吸收,释放和细胞外水平.
- 光测量反应性氧物种 (ROS) 生成,膜潜力,线粒体潜力和突触囊泡酸化.
主要成果:
- 面罩的燃烧产生了超细颗粒物.
- 暴露于这种颗粒物会显著改变神经终端中的神经递质动力学 (谷氨酸,GABA).
- 观察到神经元和线粒体膜潜力的减少和突触囊泡酸化.
- 在对刺激的反应中减少ROS生成.
结论:
- 一次性医疗面罩废物燃烧释放的神经活性超细颗粒.
- 这些颗粒对环境健康构成风险,并可能导致神经病理学.
- 强调迫切需要改善医疗口罩的废物管理,以减轻塑料污染和神经毒性风险.
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