用正念干预减少渴望物质使用障碍和行为成:随机对照试验的系统审查和元分析
Anastasia Demina1,2, Benjamin Petit3, Vincent Meille3
1Dijon University Hospital, Bâtiment Marion 14 rue Paul Gaffarel, 21079, BP77908, Dijon Cedex, France. anastasia.demina@chu-dijon.fr.
BMC neuroscience
|October 18, 2023
概括
基于正念的干预措施 (MBI) 显示了减少成欲望的潜力. 然而,目前的证据质量较低,需要进一步的高质量研究来证实它们在成治疗中的有效性.
科学领域:
- 药物中毒药物 药物中毒药物
- 成的神经生物学成的神经生物学
- 行为心理学 行为心理学
背景情况:
- 成与由负面影响驱动的自动行为有关.
- 基于正念的干预措施 (MBI) 可以解决这些神经生物学机制.
- 需要高质量的证据来证实MBI在减少渴望中的有效性.
研究的目的:
- 系统地审查和元分析MBI在减少渴望的有效性.
- 综合最近关于MBI对物质使用和行为成的数据.
主要方法:
- 随机对照试验 (RCT) 的系统审查和元分析.
- 搜索了四个数据库和三个临床试验注册表,截至2023年8月.
- 包括对药物使用障碍和行为成的MBI的研究,测量治疗后的渴望变化.
主要成果:
- 包括17个RCT,共有1228名参与者.
- 估计的整体效应大小为 -0.70 (95% CI -1.15, -0.26),有利于MBI.
- 高异质性 (I2 = 92%) 限制了关于效果大小的最终结论.
结论:
- 发现证据质量低,偏见风险高.
- 在成医学中,MBI显示出有前途的潜力.
- 需要进一步的严格研究来证实MBI在减少渴望的有效性,并解决方法上的局限性.
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