红细胞分布宽度与呼吸机相关肺炎患者30天住院死亡率之间的关系
Zhonghua Li1, Liping Yang2, Qin Xu2
1Department of Infection Management, Jiangsu Province, Taicang First People's Hospital, 58 South Changsheng Road, Taicang 215400, Taicang, No, P. R. China. lizhonghuadct@outlook.com.
高红细胞分布宽度 (RDW) 与呼吸机相关性肺炎 (VAP) 患者的30天死亡率增加有关. 作为预测重症监护室 (ICU) 住院患者死亡率的生物标志物,RDW显示出前景.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 血液学 血液学 血液学
背景情况:
- 红细胞分布宽度 (RDW) 与肺炎的结果有关.
- 在呼吸机相关肺炎 (VAP) 中RDW的预后作用仍然未被探索.
- 这项研究调查了RDW与VAP患者死亡率的关联.
研究的目的:
- 探索RDW与VAP患者住院死亡率之间的关联.
- 评估RDW对VAP患者结果的预测价值.
主要方法:
- 从MIMIC-IV数据库 (2008-2019) 中对1543名VAP患者进行了回顾性队列研究.
- 主要结局:30天住院死亡率.
- 分析包括COX回归,子组分析和ROC曲线与SOFA和SAPS II分数的比较.
主要成果:
- 在30天的住院死亡率为19.05%.
- 高RDW (≥15%) 与30天死亡率的增加显著相关 (HR=1.29,95% CI:1.01-1.63) 经过对混因素进行调整后.
- 与SOFA和SAPS II分数相比,RDW在预测死亡率方面显示出更高的预后价值.
结论:
- 较高的RDW水平与VAP患者30天住院死亡率较高有关.
- RDW是预测ICU患者的死亡率的潜在生物标志物,包括那些患有VAP的患者.
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