一个适应的算法,患者参与护理的年轻人生活在英格兰与周围艾滋病毒在英格兰
Marthe Le Prevost1, Deborah Ford2, Siobhan Crichton2
1MRC Clinical Trials Unit at University College London, 90 High Holborn, 2nd Floor, London, WC1V 6LJ, UK. m.leprevost@ucl.ac.uk.
BMC health services research
|October 18, 2023
概括
一个适应的算法有效地测量了患有围产期艾滋病毒 (YPLPHIV) 的年轻人的护理参与度 (EIC). 大多数YPLPHIV表现出良好的EIC,强调了质量数据对于准确测量的重要性.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 艾滋病毒/艾滋病管理
背景情况:
- 与艾滋病毒感染的成年人或儿童相比,患有围产期艾滋病毒 (YPLPHIV) 的年轻人参与护理 (EIC) 可能较低.
- 一个现有的EIC算法用于艾滋病毒感染的成年人被适应YPLPHIV在英格兰.
研究的目的:
- 适应和应用EIC算法来衡量英格兰YPLPHIV在护理中的参与.
- 用适应的算法和例行收集的临床数据来评估YPLPHIV的EIC.
主要方法:
- 一个成人EIC算法与当前的成人和欧洲儿科艾滋病毒指南进行了更新.
- 该算法由英国儿科/青少年艾滋病毒顾问审查和修改.
- 适应的算法应用于青少年和成年人生活与周产期艾滋病毒 (AALPHI) 队列,比较预测的访问与实际约会出席使用代理标志物,如CD4计数和病毒载荷.
主要成果:
- 这项研究分析了306个YPLPHIV在3,585个人的月内.
- 87%的月份符合参与护理的定义.
- 在未被归类为参与护理的几个月中,63%的人接受ART病毒载量≤50c/mL,27%的人接受ART病毒载量>50c/mL,10%的人没有接受ART.
结论:
- 在测量EIC时,适应的算法成功考虑了YPLPHIV的不同临床情况.
- 高质量的监测数据对于准确测量这一群体的护理参与度至关重要.
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