腹腔大动脉化在新诊断患有精性血栓塞血症的患者中
Myung-Won Lee1, Jeong Suk Koh1, Sora Kang1
1Division of Hematology/Oncology, Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea.
Blood research
|October 18, 2023
概括
腹腔大动脉化 (AAC) 在基本血栓塞动症 (ET) 患者中很普遍,并与动脉血栓事件有关. 这一发现突显了AAC作为ET的重要风险因素,强调了在诊断时评估它的必要性.
科学领域:
- 心血管医学 心血管医学
- 血液学 血液学 血液学
- 放射学 放射学是指放射学
背景情况:
- 动脉样硬化与关键血栓细胞血症 (ET) 中的动脉血栓事件有关.
- 在ET患者中,腹腔大动脉化 (AAC) 已被研究不足.
- 这项研究调查了在ET诊断时AAC的流行率和临床意义.
研究的目的:
- 为了确定腹腔大动脉化 (AAC) 在新诊断的基本血栓塞瘤 (ET) 患者的患病率.
- 确定与ET中AAC相关的风险因素.
- 评估ET中AAC和动脉血栓性血管事件之间的关联.
主要方法:
- 在2002年至2021年期间接受腹部计算机断层扫描 (CT) 的94名新诊断的ET患者的回顾性分析.
- 使用CT成像对腹部大动脉化 (AAC) 的定量评估.
- 统计分析以确定风险因素和与血栓事件的关联.
主要成果:
- 在66.0%的ET患者中检测到腹腔大动脉化 (AAC).
- 老年,较高的白细胞计数,中性粒细胞与淋巴细胞的比率升高,以及JAK2V617F阳性与AAC有关.
- AAC是发生在ET诊断之前或时发生的动脉血栓性血管事件的独立风险因素.
结论:
- 腹腔大动脉化 (AAC) 是常见的在患有基本血栓塞血症 (ET) 的患者.
- 在ET患者中,AAC与动脉血栓事件有显著的关联.
- 对AAC的评估可能对ET的风险分层有价值.
相关概念视频
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
19
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
19
Aneurysm II: Clinical Manifestations and Diagnostic Studies
10
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
10
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
11
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
11
Peripheral Artery Disease I: Introduction
9
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs but also impacts other areas, such as the arms, thereby impairing overall circulation and organ function.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty deposits inside the arterial...
9
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
14
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
14
Atherosclerosis I: Introduction
9
Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
9


