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相关概念视频

Microtubules01:35

Microtubules

There are three types of cytoskeletal structures in eukaryotic cells—microfilaments, intermediate filaments, and microtubules. With a diameter of about 25 nm, microtubules are the thickest of these fibers. Microtubules carry out a variety of functions that include cell structure and support, transport of organelles, cell motility (movement), and the separation of chromosomes during cell division.Microtubules are hollow tubes whose walls are made up of globular tubulin proteins. Each tubulin...
Studying the Cytoskeleton01:17

Studying the Cytoskeleton

The cytoskeletal architecture can be studied using different microscopic and biochemical techniques. Electron microscopy was instrumental in discovering the cytoskeletal architecture around the 1960s, which allowed obtaining structural information at a high-resolution level. However, the sample preparation procedure often limits this ability in biological samples. Several protocols have been developed over the years to optimize sample preparation. In one of the protocols known as rotary...
Assembly of Complex Microtubule Structures01:32

Assembly of Complex Microtubule Structures

Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular architecture, tracks for intracellular transport, positioning of organelles, assembly of cilia and flagella. They mediate the bipolar spindle assembly for chromosomal segregation and positioning of the cell division plate in dividing cells. The formation of microtubule complex structures depends on the cell type, cell stage, and cell function.
Microtubule Instability02:17

Microtubule Instability

Microtubules are hollow cylindrical filaments having a diameter of approximately 25 nm and a length that varies from 200 nm to 25 μm. GTP-bound tubulin subunits form αβ-heterodimers for microtubule assembly. These core building blocks interact longitudinally, polymerizing into protofilaments. The protofilaments then interact with one another through lateral bonding forces to form stable cylindrical microtubules. These cylindrical filaments are dynamic as they undergo repeated assembly and...

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相关实验视频

Updated: Jul 16, 2026

In situ Compressive Loading and Correlative Noninvasive Imaging of the Bone-periodontal Ligament-tooth Fibrous Joint
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变角度锁定系统的生物力学评估. 一个微CT分析

Jakub Glowacki1, Tomasz Bartkowiak2, Bartosz Gapinski2

  • 1Department of General Orthopaedics, Musculoskeletal Oncology and Trauma Surgery, Poznań University of Medical Sciences, Poznan, Poland.

Journal of orthopaedic trauma
|October 19, 2023
PubMed
概括

多轴锁定螺丝提供固定,但离轴插入减少曲强度. 锁盖螺丝不论角度都保持强度,显示出优越的线程合,以获得更好的结构稳定性.

关键词:
悬臂曲曲可以使用.在微型CT中使用微型CT.多轴锁定螺丝的多轴锁定螺丝

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相关实验视频

Last Updated: Jul 16, 2026

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07:09

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科学领域:

  • 整形外科手术 整形外科手术
  • 生物机械工程 生物机械工程
  • 植入物学 植入物学

背景情况:

  • 多轴锁定螺丝改善了对具有挑战性的骨库和周围假肢骨折的固定.
  • 传统的多轴系统需要在螺丝头和板孔之间进行精确的对齐.
  • 在整形外科手术中,通过多轴固定确保结构完整性至关重要.

研究的目的:

  • 评估各种多轴锁定螺丝系统的机械性能.
  • 为了将螺丝板的合参数与机械性能联系起来.
  • 评估插入角度对结构强度的影响.

主要方法:

  • 测试在0,5,10和15度的角度插入螺丝的多轴系统.
  • 微计算机断层扫描 (micro-CT) 用于在螺丝板接口上量化平均线程接触 (ATE).
  • 吊杆曲测试以确定结构强度.
  • 扫描电子显微镜用于详细的接口检查.

主要成果:

  • 在所有系统中,标准 (0度) 插入的最大曲强度是最高的.
  • 外轴插入显著降低了点装载线进和切入螺丝的曲强度.
  • 锁帽螺丝显示出不变的曲强度,无论插入角度如何.
  • 微CT证实了离轴螺丝的ATE降低,锁盖机制显示了最高的ATE.

结论:

  • 多轴锁板的机械性能可能会因轴外插件的曲强度降低而受到损害.
  • 在确定插入参数时,外科医生应考虑每个多轴系统的特定特征.
  • 锁帽螺丝设计似乎在不同的插入角度提供了更强大的性能.