在患有亚洲坑蛇 (Gloydius) 毒毒的狗中进行血栓结晶学评估
Jeong-Min Lee1,2, Youn-Seo Jung1, Yeon-Ju Kim1
1Korea Animal Medical Center, Cheongju, South Korea.
The Journal of veterinary medical science
|October 19, 2023
概括
亚洲坑蛇 (Gloydius) 对狗的中毒会导致低凝血状态,由改变的血栓凝结学 (TEG) 变量和血小板数量的减少表明. 这些发现表明TEG可以帮助诊断和监测受影响的狗的凝血病.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 毒理学 毒理学 毒理学
- 血液学 血液学 血液学
背景情况:
- 蛇毒是兽医界的一个重要问题.
- 众所周知,亚洲坑蛇 (Gloydius) 可以引起凝血病.
- 血小板造影 (TEG) 是评估血液静止的一个有价值的工具.
研究的目的:
- 为了研究亚洲坑蛇 (Gloydius) 毒害对TEG变量和狗血小板计数的影响.
- 为了比较TEG参数和有毒狗和健康对照之间的血小板计数.
- 为了确定亚洲坑蛇毒害是否会导致狗的低凝血状态.
主要方法:
- 一项比较研究涉及十只已确认亚洲坑蛇 (Gloydius) 毒害的狗和二十只健康的对照狗.
- 进行血小板造影 (TEG) 来分析包括G,最大幅度 (MA),角度值,K值和R值在内的变量.
- 在所有狗中测量了血小板计数.
主要成果:
- 患有亚洲坑蛇毒害的狗在G,最大幅度 (MA),角度值和血小板数量显著下降.
- 与对照组相比,受毒狗的K值和R值显著增加.
- 这些结果表明,在亚洲坑蛇中毒后,狗的低凝血状态.
结论:
- 亚洲坑蛇 (Gloydius) 的中毒诱导了狗的低凝血状态.
- 血小板表 (TEG) 变量和血小板计数在毒化后发生显著变化.
- TEG可能是一个有用的诊断和监测工具,用于亚洲坑蛇中毒的狗的凝血病.
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