首先是酒精,最后是大麻:在同时使用酒精和大麻的个人中确定一种特别危险的使用模式
Hollis C Karoly1, Mark A Prince1, Bradley T Conner1
1Department of Psychology, Colorado State University, Fort Collins, Colorado, USA.
Substance use & misuse
|October 19, 2023
概括
酒精和大麻的共同使用是常见的. 药物使用的顺序,特别是首先是酒精和最后是大麻,与更高的大麻使用障碍得分和更少的积极后果有关,特别是在典型的几周.
科学领域:
- 药物成科学 药物成科学
- 大麻研究 大麻研究
- 药物使用研究 药物使用研究
背景情况:
- 酒精和大麻的共同使用很普遍,增加了负面后果和依赖的风险.
- 诸如delta-9-tetrahydrocannabinol (THC) 的剂量和物质顺序等因素会影响联合使用的结果.
- 关于社区样本中的这些细微关系的研究有限.
研究的目的:
- 调查酒精和大麻联合使用对物质使用结果的影响.
- 探索THC剂量和共同使用模式在社区样本中的作用.
- 检查与性别和年龄的相互作用,与共用有关.
主要方法:
- 从大麻药房招募的87名社区成员的调查数据.
- 回归分析 (OLS,负二项式,censor-inflated) 用于建模关系.
- 检查共同使用的订单模式,THC剂量,大麻的结果,以及与性别和年龄的相互作用.
主要成果:
- 共同使用者报告大麻使用障碍识别测试 (CUDIT) 得分明显高于非共同使用者.
- "首先是酒精,最后是大麻" (AFCL) 模式在女性中更为常见,并且与较高的CUDIT分数和较少的积极后果有关.
- 其他共同使用模式在大量使用周期间预测了更高的CUDIT分数.
结论:
- 同时使用的顺序模式与物质使用结果有很大关系,包括大麻使用障碍的严重程度.
- AFCL模式显示了与CUDIT分数和积极后果的明显关联.
- 需要进一步的纵向研究来确定因果关系.
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