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吸烟和尼古丁产品消费与神经感官听力损失的关联:人口层面的分析
Marwin Li1, Natalie M Perlov1, Jena Patel2
1Sidney Kimmel Medical College, Thomas Jefferson University.
概括
尼古丁和烟草产品的使用,包括香烟和烟,显著增加了年轻成年人发展神经感官听力损失 (SNHL) 的风险. 即使没有使用产品,老年人也显示出更高的SNHL概率.
科学领域:
- 听力学 听力学是指听力学.
- 公共卫生 公共卫生
- 毒理学 毒理学 毒理学
背景情况:
- 感官神经听力损失 (SNHL) 是一个日益严重的公共卫生问题.
- 尼古丁和烟雾暴露对听力健康的影响,特别是在年轻人群中,需要进一步研究.
研究的目的:
- 调查香烟,尼古丁制品和大麻的使用与感觉神经听力损失 (SNHL) 的发生率之间的联系.
- 为了确定含有高尼古丁含量或类似香烟烟雾的产品是否会增加年轻人群中SNHL发展的可能性.
主要方法:
- 从2003年到2022年,使用TrinetX美国协作网络进行了一项回顾性队列研究.
- 分析了大约360万18岁及以上的患者.
- 倾向性得分匹配用于控制诸如糖尿病和缺血性疾病等混因素.
主要成果:
- 在使用任何尼古丁产品的18-54岁个体中,患SNHL的几率增加了5.91倍.
- 像烟 (9.04倍) 和香烟 (4.00倍) 等特定产品表明与SNHL有显著的关联.
- 大麻使用者也表现出更高的SNHL几率 (3.99倍),而没有使用产品的老年人 (55岁以上) 也有更高的风险 (4.73倍).
结论:
- 尼古丁和烟雾暴露与增加患SNHL风险密切相关.
- 在研究的产品中,烟与SNHL的关联最为显著.
- 这些发现强调了各种物质使用模式的耳毒性潜力,包括尼古丁和大麻.
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