一个患有中性细胞丰富的无细胞大细胞淋巴瘤的病例,复发
Jung Eun Seol1, Seong Min Hong1, Sang Woo Ahn1
1Department of Dermatology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Annals of dermatology
|October 19, 2023
概括
富含中性粒细胞的形大细胞淋巴瘤 (ALCL) 是一种罕见的变异,经常复发. 这一案例突出显示了中性粒细胞丰富的ALCL在系统上复发两次的第一个实例.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 皮肤病理学 皮肤病理学
背景情况:
- 无细胞大细胞淋巴瘤 (ALCL) 包含了几种组织学变异,包括罕见的富含中性粒细胞的亚型.
- 富含中性粒细胞的ALCL的特征是CD30阳性瘤细胞和显著的中性粒细胞透,通常呈现为原发性皮肤ALCL (pcALCL).
研究的目的:
- 报告中性粒细胞丰富ALCL的第一个病例,第二次系统性复发.
- 讨论这种罕见变种及其复发模式的临床和组织病理特征.
主要方法:
- 组织病理学检查瘤细胞和透的炎症细胞.
- 对临床病史的审查,包括ALCL的诊断,治疗和复发.
- 与之前报告的中性粒细胞丰富的ALCL复发病例的比较.
主要成果:
- 一名63岁的男性有腹部pcALCL病史,出现了一块腿部质量,诊断为富含中性粒细胞的ALCL.
- 该患者在左支气管中出现了系统性ALCL (sALCL) 的复发,在治疗后实现了缓解.
- 这是第一个报告中性粒细胞丰富的ALCL系统性复发的第二次病例.
结论:
- 富含中性粒细胞的ALCL虽然对治疗有反应,但倾向于复发.
- 富含中性粒细胞的ALCL系统性复发是不常见的,而这种情况是第二次系统性复发的第一个记录例.
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