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相关概念视频

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Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
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Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
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Assessing the respiratory rate and rhythm for a complete minute is crucial for evaluating the breathing pattern. Even a minor increase in the patient's average respiratory rate, by as little as three to five breaths per minute, is an early and vital indicator of respiratory distress. Patients with a respiratory rate exceeding twenty-four breaths per minute require close monitoring to determine the physiological alterations. This careful observation is essential for prompt recognition and...
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相关实验视频

Updated: Jul 13, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
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在患有阻塞性睡眠呼吸暂停的儿童中进行计算流体动力学研究.

Wei-Chung Hsu1,2,3, Kun-Tai Kang1,4,5, Yunn-Jy Chen3,6

  • 1Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan.

Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
|October 19, 2023
PubMed
概括

计算流体动力学 (CFD) 可以确定阻塞性睡眠呼吸暂停 (OSA) 的儿童的呼吸道差异. 在OSA患者中较高的气道压力和阻力表明CFD是一种有价值的诊断工具.

关键词:
孩子孩子孩子孩子孩子孩子圆束计算机断层扫描技术压力 压力 压力 压力 压力电阻的阻力可以睡眠呼吸暂停综合征上空气道上空气道上空气道速度的速度是速度的速度.

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科学领域:

  • 儿科肺病学 儿科肺病学
  • 医疗成像医学成像
  • 生物医学工程 生物医学工程

背景情况:

  • 阻塞性睡眠呼吸暂停 (OSA) 是儿童常见的疾病.
  • 准确的OSA诊断依赖于对上呼吸道通透性的客观测量.
  • 基于图像的计算流体动力学 (CFD) 提供了一种非侵入性的方法来评估气道动力学.

研究的目的:

  • 在被诊断患有阻塞性睡眠呼吸暂停 (OSA) 的儿童中识别基于图像的计算流体动力学 (CFD) 特性.
  • 评估CFD在区分患有OSA和患有初级打的儿童中的实用性.

主要方法:

  • 一项涉及医院儿童队列的诊断研究,这些儿童有暗示OSA的症状.
  • 三维CFD模型是从圆束计算机断层扫描 (CBCT) 中生成的.
  • 聚梦摄影用于诊断OSA,并根据呼吸暂停-呼吸暂停指数 (AHI) 将参与者分类.

主要成果:

  • 与初级打 (AHI < 1) 的儿童相比,患有中度至严重的OSA (AHI > 5) 的儿童的呼吸道总压力,呼吸道总阻力和最小截面面积的速度显著更高.
  • 为了确定中度至重度的OSA,最优的切线点被确定为气道总压力 (46.2Pa),气道总阻力 (2373Nm) 和最小截面面积 (12.6m/s) 的速度.
  • 条件后勤回归证实,这些CFD参数与中度至重度OSA的风险增加有显著的关联.

结论:

  • 基于图像的计算流体动力学 (CFD) 是评估儿科OSA上呼吸道通透性的有希望的工具.
  • 像气道压力,阻力和速度这样的CFD参数可以帮助诊断儿童的OSA和风险分层.
  • 进一步的研究可以探索将CFD整合到OSA评估的常规临床实践中.