Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Jul 12, 2025

Measuring Caenorhabditis elegans Life Span on Solid Media
12:49

Measuring Caenorhabditis elegans Life Span on Solid Media

Published on: May 12, 2009

30.0K

轻松的C. 轻松的 elegans 虫寿命绘图和统计使用WLSplot.

Blaise L Mariner1,2, Jack Peterson1, Jackson C Taylor1

  • 1Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, New Mexico, United States.

microPublication biology
|October 19, 2023
PubMed
概括
此摘要是机器生成的。

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Increased FICD-mediated protein AMPylation triggers conserved endoplasmic reticulum stress signaling across species.

Cell stress & chaperones·2026
Same author

Novel tRNA Synthetase Inhibitors Increase Healthspan, Lifespan, and Autophagic Flux in <i>C. elegans</i>.

Biomolecules·2026
Same author

Diverse Patterns of Allele-Specific Expression in Healthy Human Tissues.

bioRxiv : the preprint server for biology·2025
Same author

Protein Catabolites as Blood-Based Biomarkers of Aging Physiology: Findings From the Dog Aging Project.

Aging cell·2025
Same author

Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity.

Cell reports·2025
Same author

Targeting DTX2/UFD1-mediated FTO degradation to regulate antitumor immunity.

Proceedings of the National Academy of Sciences of the United States of America·2024
Same journal

Complete Genome Sequence of <i>Rhodococcus equi</i> Phage Nova53.

microPublication biology·2026
Same journal

Modeling Inherited Methylmalonic Acidemia Using Isogenic Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mutations in <i>Methylmalonyl-CoA Mutase</i>.

microPublication biology·2026
Same journal

Invasive African fig flies ( <i>Zaprionus indianus</i> ) have reduced cold acclimation ability compared to cosmopolitan drosophilid species.

microPublication biology·2026
Same journal

An activating mutation in AGEF-1, a putative Arf GEF, causes yolk extrusion from <i>C. elegans</i> embryos.

microPublication biology·2026
Same journal

Diel Activity Patterns of Bobcats and Domestic Cats in the Houston Metropolitan Area.

microPublication biology·2026
Same journal

Exploring the Effects of Antioxidants on αSynuclein-Induced Motor Deficits in <i>Drosophila</i> Larvae.

microPublication biology·2026
查看所有相关文章

WLSplot是一个新的R包,简化了对生存数据的分析和图形显示,特别是对于Caenorhabditis elegans寿命研究. 它自动化统计信息,并生成可编辑的图表,以方便解释和进一步研究.

科学领域:

  • * 生物学 * 生物学
  • * 生物信息学是一门学科.
  • * 遗传学 在遗传学方面

背景情况:

  • *分析寿命数据,特别是对像Caenorhabditis elegans这样的模型生物,需要专门的工具来准确地解释统计数据和图形表示.
  • * 现有的方法可能缺乏用于自动统计注释和可定制图谱生成的集成功能.
  • * 有关关键的统计见解有效地可视化生存曲线对于理解对寿命的遗传或环境影响至关重要.

研究的目的:

  • * 推出WLSplot,一个R包,旨在简化对寿命存活数据的分析和图形可视化.
  • *为研究人员提供一个用户友好的功能,通过集成的统计信息自动生成生存曲线.
  • * 促进各种实验设置的分析,包括RNAi,基因型和药物治疗,重点是*Caenorhabditis elegans*.

主要方法:

  • *开发一个R包,WLSplot,包含一个单一的功能,用于全面的寿命数据分析和绘图.
  • * 集成自动化统计计算,包括对照组的显著性测试 (p值和星号).
  • *生成可编辑的可扩展矢量图形 (SVG) 格式的输出,以进行进一步的定制和数据摘要,以进行高级操作.

主要成果:

  • * WLSplot成功地批量分析和绘制多个寿命实验图,精确地斜体化基因名称.

更多相关视频

The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan
11:58

The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan

Published on: June 29, 2018

9.5K
Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
10:08

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Published on: May 18, 2022

3.4K

相关实验视频

Last Updated: Jul 12, 2025

Measuring Caenorhabditis elegans Life Span on Solid Media
12:49

Measuring Caenorhabditis elegans Life Span on Solid Media

Published on: May 12, 2009

30.0K
The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan
11:58

The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan

Published on: June 29, 2018

9.5K
Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
10:08

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Published on: May 18, 2022

3.4K
  • *当观察到与对照的差异时,该包会自动为生存曲线传说添加意义指标 (星号和p值).
  • *输出提供可编辑的SVG文件,以及数据摘要,使得下游分析和呈现灵活.

    • 结论:

    • * WLSplot为分析和可视化*Caenorhabditis elegans*寿命数据提供了强大而高效的解决方案.
    • * 该软件包简化了复杂的生存数据分析,使其对具有不同统计专业知识的研究人员可访问.
    • * WLSplot通过提供准备发布,可编辑的图形输出,并集成统计意义来增强数据的解释能力.