面向有效的,基于吸附的防拉链刷:pH,盐和聚合物设计的影响
Anna M C Maan1, Anton H Hofman1, Théophile Pelras2
1Polymer Science, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
概括
我们优化了聚合物刷涂层,以防止表面污染. 调整聚合物的特性和条件,如pH值和盐度,显著提高了防性能,达到99%以上的抗蛋白吸附效率.
科学领域:
- 表面科学与工程 表面科学与工程
- 材料化学 材料化学
- 生物材料和涂料
背景情况:
- 表面污染是各行各业普遍存在的问题,导致材料退化和运营效率低下.
- 聚合物刷,特别是末端移植聚合物,提供了一个有前途的策略,以创建防表面.
- 基于吸附的方法制造聚合物刷是有吸引力的,因为他们的可扩展性和简单性.
研究的目的:
- 显著改进制造基于块共聚合物的防涂层的两步吸附策略.
- 系统地调整pH,盐度和聚合物设计等参数,以优化防效率.
- 了解聚合物架构,表面特性和防性能之间的关系.
主要方法:
- 一个两步吸附过程,涉及带有疏水电荷的双块共聚物微粒作为原料.
- 复合相反充电的抗污染双块共聚合物到原料层上,以形成聚合物刷.
- 系统地改变pH值,盐度 (1mM) 和聚合物块比 (疏水/疏水) 以优化刷子的形成和性能.
主要成果:
- 增加原料菌的疏水/亲水块比提高了表面吸附,导致更密,更均,更亲水的原料层.
- 由于高效的弱聚电解质块复合,可以达到接近中性pH和低盐度 (1mM) 的最佳抗效.
- 调整聚电解质块的比率增加了刷子密度和防性能;替代防块进一步增强了性能 (>99%的酶,87%的BSA).
结论:
- 基于吸附的优化拉链刷策略提供了一种高效的方法,用于创建坚固的防表面.
- 参数调整,包括聚合物设计和溶液条件,对于最大限度地提高防性能至关重要.
- 这种方法提供了一个可扩展和多功能平台,用于开发具有高效率的先进防涂层.
相关概念视频
Buffer Effectiveness
Buffer solutions do not have an unlimited capacity to keep the pH relatively constant . Instead, the ability of a buffer solution to resist changes in pH relies on the presence of appreciable amounts of its conjugate weak acid-base pair. When enough strong acid or base is added to substantially lower the concentration of either member of the buffer pair, the buffering action within the solution is compromised.
The buffer capacity is the amount of acid or base that can be added to a given volume...
The buffer capacity is the amount of acid or base that can be added to a given volume...
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Waterproofing admixtures render concrete hydrophobic,...
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