相关实验视频

Updated: Jul 12, 2025

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies

Published on: October 22, 2014

阻塞性睡眠呼吸暂停对视网膜微血管结构的影响

Müjdat Karabulut¹, Semai Bek², Sinem Karabulut¹

¹Ophthalmology Department, Mugla Sıtkı Kocman University Training and Research Hospital, Mugla 48300, Türkiye.

International journal of ophthalmology

|October 19, 2023

概括

阻塞性睡眠呼吸暂停综合征与视网膜微血管密度降低有关. 更高的呼吸暂停严重程度与表面和深层毛细血管的血管密度下降相关.

科学领域:

眼科医生眼科眼科
睡眠医学睡眠医学
心血管研究研究心血管研究

背景情况:

阻塞性睡眠呼吸暂停综合征 (OSAS) 是一种与全身健康问题相关的普遍疾病.
视网膜微血管结构的变化可以作为OSAS患者系统性血管变化的指标.

研究的目的:

调查和量化被诊断患有阻塞性睡眠呼吸暂停综合征的患者视网膜微血管变异.
探索OSAS的严重程度和特定的视网膜血管参数之间的相关性.

主要方法:

一项前性,观察性病例控制研究,比较健康人与OSAS患者在轻度,中度和重度类别.
光学连贯断层扫描血管造影 (OCTA) 用于评估血管参数,包括状血管面积和斑点区域的血管密度.
分析侧重于6.00×6.00毫米2扫描面积内的表面和深层毛细管.

主要成果:

与健康对照组相比,患有OSAS的患者在表面和深层毛细血管中表现出明显较低的血管密度 (P<0.05).
呼吸暂停-呼吸暂停指数 (AHI),特别是在快速眼动 (REM) 睡眠期间,显示出与各种视网膜区域的血管密度有显著的反向相关性 (P<0.05).
非REM AHI还表明,在两个毛细管中,对状血管密度存在显著的反相关性.

结论:

这项研究表明,在患有阻塞性睡眠呼吸暂停综合征的患者中,视网膜微血管密度减少.
在OSAS的严重程度 (以AHI表示) 和视网膜血管密度之间存在显著的反向关系,这表明OSAS会影响眼血管系统.

关键词:

呼吸暂停-呼吸暂停指数深层的毛细血管.阻塞性睡眠呼吸暂停症是什么视网膜微血管学表面的毛细血管.船舶密度是指船舶的密度.

更多相关视频

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents

Published on: September 16, 2020

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

相关概念视频

Sleep Apnea

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...