在沙特阿拉伯吉达市成年人中分析COVID-19疫苗接种副作用
Turki Alamri1, Fahad Anwer1, Nadeem S Butt1
1Department of Family and Community Medicine, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah, SAU.
Cureus
|October 19, 2023
概括
这项研究调查了沙特阿拉伯的Pfizer-BioNTech疫苗副作用,发现第一剂后的疲劳和发烧很常见. 了解这些疫苗副作用有助于做出明智的决策.
科学领域:
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
- 药物监督 药物监督 药物监督
背景情况:
- COVID-19大流行突显了疫苗的关键作用,瑞-生物科技mRNA疫苗在全球获得了突出地位.
- 在全球和沙特阿拉伯,人们仍然担心疫苗的安全性和有效性.
- 之前的研究发现了副作用,包括罕见的心肌炎病例,需要进一步调查疫苗不良事件.
研究的目的:
- 系统地调查瑞-生物科技疫苗接种后的症状,包括三剂.
- 探索症状的持续时间,医疗保健的利用,以及接种疫苗后的自我解决.
- 分析不同年龄组和疫苗剂量的COVID-19感染率.
主要方法:
- 在沙特阿拉伯吉达进行了一项在线横截面调查.
- 332名参与者完成了一项关于他们接种疫苗经验的自我报告调查.
- 收集的数据包括报告的症状,持续时间和寻求医疗保健的行为.
主要成果:
- 疲劳和发烧是最常见的概括副作用;注射部位反应,肌肉和关节疼痛是常见的局部副作用.
- 与AstraZeneca相比,第一剂Pfizer疫苗接种与疲劳和发烧有显著的关联.
- 在所有疫苗剂量中,中年成人 (31-45岁) 的COVID-19感染率较低,老年人 (46-60岁) 的感染率更高.
结论:
- 这项研究提供了宝贵的见解,了解瑞-生物科技疫苗的现实世界副作用概况.
- 医疗保健专业人员和接种疫苗的人员可以使用这些信息来做出明智的决策和管理不良反应.
- 针对感染的疫苗有效性观察到与年龄相关的差异,这需要进一步研究.
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