混合螺旋扫描在双层覆盖的基于纤维的手持共聚焦扫描光眼镜
Franklin Wei1,2, Kristen Hagan1, Christian Viehland1
1Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Biomedical optics express
|October 19, 2023
概括
一个新的手持式扫描光眼镜 (SLO) 系统使用了一种新的混合螺旋扫描模式,用于更快,更容易访问的视网膜成像. 这项创新改善了对糖尿病视网膜病变等眼睛疾病的查.
科学领域:
- 眼科和生物医学工程眼科和生物医学工程
- 医学成像技术 医学成像技术
背景情况:
- 高速,可访问的视网膜成像对于早期检测糖尿病视网膜病变和与年龄有关的黄斑变性等病理至关重要.
- 扫描光眼镜 (SLO) 提供优越的图像质量比传统的 fundus 摄像机,但往往受到桌面设计和低效的光扫描模式的限制.
- 在SLO中进行晶格扫描可能会导致眼睛运动,降低图像质量和选设置中的实用性.
研究的目的:
- 开发一种新的,便携式和强大的手持式扫描光眼镜 (SLO) 系统.
- 引入和实施新的"混合螺旋"扫描模式,以提高效率和减少对象的眼动.
- 为了证明这种手持系统在体内视网膜成像中的可行性.
主要方法:
- 为SLO开发一种新的混合螺旋扫描模式.
- 一个完整的手持式HSS-SLO系统的设计,具有使用双覆盖纤维 (DCF) 的便携式光纤合患者接口.
- 实时图像重建技术的实施用于混合螺旋扫描.
主要成果:
- 成功开发和实施了一种手持式混合螺旋扫描SLO系统 (HSS-SLO).
- 该系统采用强大的单路径光学拓,以稳定地对照和收集.
- 通过成功的8名人类志愿者的体内成像来证明可行性.
结论:
- 新型手持HSS-SLO系统为可访问和高效的视网膜成像提供了有前途的进步.
- 混合螺旋扫描模式解决了传统状扫描的局限性,提高了疾病查的可用性.
- 这项技术有可能显著改善各种视网膜病理的查和管理.
更多相关视频
12:54Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo
Published on: October 2, 2021
3.3K
06:19In Vivo Imaging of Cx3cr1gfp/gfp Reporter Mice with Spectral-domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy
Published on: November 11, 2017
10.7K
相关概念视频
Confocal Fluorescence Microscopy
13.3K
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
13.3K
Phase Contrast and Differential Interference Contrast Microscopy
8.1K
Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
8.1K
