在定量微弹性绘图中对摩擦的分析
Kai L Metzner1,2, Qi Fang1,2, Rowan W Sanderson1,2
1BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands, and Centre for Medical Research, The University of Western Australia, Perth, WA 6009, Australia.
Biomedical optics express
|October 19, 2023
概括
摩擦显著影响定量微弹性图 (QME) 的准确性. 优化滑协议可确保可靠的弹性测量,这对于微尺度组织力学至关重要.
科学领域:
- 生物医学工程 生物医学工程
- 光学一致性弹性图形 弹性图形
- 生物物理学的生物物理.
背景情况:
- 定量微弹性图 (QME) 测量微尺度组织的机械性质.
- 在QME中的接触接口上的摩擦可以在弹性估计中引入重大错误.
- 在QME中摩擦的精确影响还没有得到很好的描述.
研究的目的:
- 系统地分析摩擦对QME测量的影响.
- 在QME中确定影响摩擦和弹性精度的实验因素.
- 为准确的QME开发和验证一个优化的滑协议.
主要方法:
- 在受控实验中利用了化物幽灵.
- 研究了滑剂粘度,机械对比度和压缩时间对摩擦的影响.
- 将QME弹性测量与单轴压缩测试进行比较.
- 评估了一种针对精度优化的滑协议.
主要成果:
- 发现摩擦效应取决于滑剂粘度,机械对比度和压缩持续时间.
- 在没有适当的滑的情况下,观察到超过一个数量级的弹性误差.
- 一个优化的滑协议实现了<10%的误差,对样品的Young的模块从3kPa到130kPa.
- 摩擦被证明可以减少QME的机械对比度.
结论:
- 摩擦是影响QME准确性的关键因素,必须仔细管理.
- 一个优化的滑策略可以使用QME.me进行强大而准确的弹性测量.
- 已建立的框架可以应用于其他接触弹性技术,以了解摩擦效应.
相关概念视频
Characteristics of Dry Friction
601
Dry friction occurs when two solid surfaces slide against each other without any lubrication or fluid present. It causes resistance when pushing objects along a surface, like a gardener pushing a wheelbarrow. The force applied to move the cart causes dry friction between the wheel and the ground.
Before the wheelbarrow starts moving, the static frictional force acts tangentially to the contact surface, opposing the force that is about to induce the motion. This frictional force prevents the...
Before the wheelbarrow starts moving, the static frictional force acts tangentially to the contact surface, opposing the force that is about to induce the motion. This frictional force prevents the...
601
Frictional Force
8.1K
When a body is in motion, it encounters resistance because the body interacts with its surroundings. This resistance is known as friction, a common yet complex force whose behavior is still not completely understood. Friction opposes relative motion between systems in contact, but also allows us to move. Friction arises in part due to the roughness of surfaces in contact. For one object to move along a surface, it must rise to where the peaks of the surface can skip along the bottom of the...
8.1K
Dry Friction
399
Dry friction occurs between two solid surfaces in contact as they attempt to move relative to one another. In daily life, dry friction is encountered in various forms, such as when walking on the ground, sliding an object across a table, or rubbing hands together. Despite its ubiquity, the underlying mechanisms behind dry friction are not readily visible.
To illustrate this concept, imagine a wooden crate resting on a rough, non-uniform horizontal surface. When an external force is applied to...
To illustrate this concept, imagine a wooden crate resting on a rough, non-uniform horizontal surface. When an external force is applied to...
399
Types of Friction Problems
549
Friction is an essential concept in physics, engineering, and everyday life. It is the force that opposes the relative motion or tendency of such motion between two surfaces in contact. One of the most common types of friction encountered in various applications is dry friction. Dry friction problems can be broadly categorized into three types, each with unique characteristics and challenges.
The first type of dry friction problem involves situations where there is no apparent impending motion....
The first type of dry friction problem involves situations where there is no apparent impending motion....
549
Friction: Problem Solving
251
Friction is an essential force that influences the motion of objects in daily life. Depending on the situation, it can be either beneficial or problematic. Consider a bus with a mass of three megagrams and its center of mass at a specific point, moving along a banked road at a constant speed. The coefficient of static friction between the tires and the road is 0.5. Find the maximum angle of the banked road at which the bus would not slip or tip.
Initially, a visual representation of the...
Initially, a visual representation of the...
251
Static and Kinetic Frictional Force
16.0K
One of the simpler characteristics of sliding friction is that it is parallel to the contact surfaces between systems, and is always in a direction that opposes the motion or attempted motion of the systems relative to each other. If two systems are in contact and moving relative to one another, then the friction between them is called kinetic friction. For example, kinetic friction slows a hockey puck sliding on ice.
However, if two systems are in contact and are stationary relative to one...
However, if two systems are in contact and are stationary relative to one...
16.0K


