适应平衡检测光谱域光学连贯性断层扫描
David A Miller1, Roman Kuranov1,2, Hao F Zhang1
1Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Biomedical optics express
|October 19, 2023
概括
我们开发了一种适应平衡方法,用于光谱域平衡检测光学连贯性断层扫描 (SD-BD-OCT). 这种技术通过准确调整光谱数据而提高成像质量,而无需预校准,提高了噪声抑制.
科学领域:
- 生物医学光学 生物医学光学
- 医学成像技术 医学成像技术
- 光学工程是指光学工程.
背景情况:
- 平衡检测光学连贯性断层扫描 (BD-OCT) 尽量减少光源噪声,以增强成像效果.
- 光谱域BD-OCT (SD-BD-OCT) 需要两个光谱仪之间的精确光谱共同记录,以有效抑制噪声.
- 目前的共同注册方法需要预校准或主观后处理,这限制了它们的适用性.
研究的目的:
- 为SD-BD-OCT引入一种自适应子像素匹配方法,称为自适应平衡.
- 为了使准确的光谱共同记录能够独立于相对强度噪声 (RIN) 或信号水平.
- 消除 SD-BD-OCT 数据处理中预校准的需要.
主要方法:
- 在SD-BD-OCT中开发了一个适应平衡算法,用于分像素光谱匹配.
- 将该方法应用于具有不同光谱仪相机增益,曝光时间和激光重复率的数据集.
- 使用幻影成像和人类视网膜扫描对现有方法进行性能评估.
主要成果:
- 适应平衡实现了与现有方法相比的或优于现有方法的性能.
- 该技术在各种成像条件和参数中表现出强度.
- 在人类视网膜成像中的成功应用突出了其实用的实用性.
结论:
- 适应平衡为SD-BD-OCT中频谱共同注册提供了多功能和有效的解决方案.
- 这种方法通过改善RIN抑制而提高图像质量,而无需预校准.
- 适应平衡方法扩大了高性能BD-OCT在生物医学成像中的适用性.
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