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Updated: Jul 12, 2025

Large-scale Gene Knockdown in C. elegans Using dsRNA Feeding Libraries to Generate Robust Loss-of-function Phenotypes
18:38

Large-scale Gene Knockdown in C. elegans Using dsRNA Feeding Libraries to Generate Robust Loss-of-function Phenotypes

Published on: September 25, 2013

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在Caenorhabditis elegans系统性RNAi中出口沉默RNA的独特途径

Keita Yoshida1, Yuji Suehiro1, Katsufumi Dejima1

  • 1Department of Physiology, Tokyo Women's Medical University School of Medicine, 8-1, Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.

iScience
|October 19, 2023
PubMed
概括

研究人员确定了REXD-1和TBC-3的新因子,它们与SID-5合作,在线虫Caenorhabditis elegans中传播双链RNA (dsRNA),从而使系统性RNA干扰 (RNAi) 成为可能. 这一发现揭示了通过RNA分子进行的细胞间通信.

关键词:
生物化学 生物化学生物科学 生物科学细胞生物学 细胞生物学遗传学 遗传学 是一个分子生物学分子生物学自然科学 自然科学

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