亚洲色素大米生物活性化合物的益处及其对乳腺癌的影响:系统性审查
Wirdatun Nafisah1, Alexander Patera Nugraha2, Aditya Nugroho3
1Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Brawijaya, Malang, East Java, 65145, Indonesia.
F1000Research
|October 19, 2023
概括
亚洲色素大米中的生物活性化合物显示出降低乳腺癌风险的潜力. 这一系统性审查强调了它们的抗癌性质,表明有色素大米在预防癌症方面发挥了有益的作用.
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 食品科学 食品科学 食品科学
背景情况:
- 颜料大米含有具有潜在健康益处的生物活性化合物.
- 降低乳腺癌风险是一个重要的公共卫生问题.
研究的目的:
- 系统地审查有关亚洲色素大米生物活性化合物的益处的文献.
- 探索这些化合物在乳腺癌预防和治疗中的影响.
主要方法:
- 在Scopus和PubMed数据库中进行系统的文献搜索.
- 纳入标准侧重于2013-2020年间发表的研究,不包括较旧的,非英语或书章文章.
- 最终选择符合所有纳入标准的10份全文手稿.
主要成果:
- 包含的研究是基于亚洲的,发表于2013-2020年,主要使用黑色,红色或韩国色素水提取物.
- 已识别的生物活性化合物包括安东,丁-3-葡萄糖化物,丁-3-葡萄糖化物,g-oryzanol和g-tocotrienol.
- 这些化合物在体外和体内都对乳腺癌细胞表现出了亲亡,抗增殖和抗转移的作用.
结论:
- 颜料大米含有生物活性化合物,具有预防乳腺癌的重大潜力.
- 对特定化合物和机制的进一步研究是有必要的.
- 饮食中添加有色素大米可能有助于降低乳腺癌风险.
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