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身体,心理和生化恢复从类固醇诱导的阴性腺体缺陷症:一个范围审查
Pravik Solanki1,2, Beng Eu3,4, Jeremy Smith5
1Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia.
代谢类固醇滥用可能会导致阴性腺体缺陷症,恢复因个人因素而异. 身体的恢复需要几个月到几年,而心理的恢复是不太了解,而妇产不良可能不会解决.
科学领域:
- 内分泌学 在内分泌学.
- 安德罗学与人类学
- 运动医学 运动医学
背景情况:
- 代谢类固醇的滥用经常导致过低性.
- 有限的数据存在于合成代谢类固醇诱导的低子腺体主义 (ASIH) 的自然恢复模式.
- 了解ASIH恢复对于使用者和临床医生管理禁用雄激素滥用药物至关重要.
研究的目的:
- 综合关于ASIH的身体,心理和生化恢复模式的证据.
- 为帮助患者从AAS滥用中恢复的临床医生提供参考资料.
主要方法:
- 在超生理性丸激素暴露后,对下丘脑-垂体-丸激素轴的文献综述.
- 对从PubMed中恢复ASIH的观察和干预研究的范围审查.
- 综合发现用于临床参考.
主要成果:
- 身体恢复 (丸缩,精子生成) 通常会在几个月到几年内发生.
- 性欲可能会在几个月内恢复,通常不如AAS使用时那么强大.
- 妇科复苏不太可能;心理恢复数据不足,表明暂时的戒断与潜在的持久较轻的症状.
- 生物化学恢复显示在几个月内几乎完全恢复丸激素,并在3-6个月内完全恢复淋巴激素.
结论:
- ASIH的恢复是可变的,受年龄和虐待严重程度的影响.
- 完全康复的时间表在身体,心理和生化参数上有所不同.
- 需要进一步的前性研究来准确地描述ASIH恢复轨迹.
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