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Updated: Jul 12, 2025

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基于分子对接和分子动力学模拟的蛋白质L亲和染色体的配体的计算设计

Saman Rahmati1, Kowsar Bagherzadeh2,3, Seyed Shahriar Arab4

  • 1Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.

Journal of biomolecular structure & dynamics
|October 19, 2023
PubMed
概括

工程蛋白 L B 域显示对抗体碎片增强的结合亲和力. 分子模拟和同质模型创造了稳定的,高亲和度的蛋白质L变体,以改善抗体净化.

关键词:
蛋白质 L 是一种蛋白质.亲缘关系染色学 亲缘关系染色学抗体碎片 抗体碎片分子对接;分子动力学模拟模拟.

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