相关实验视频
Updated: Jul 12, 2025

07:57
A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
21.0K
甲状腺功能低下症,并发症和与健康有关的生活质量:基于人口的研究
Hanneke J C M Wouters1,2, Bruce H R Wolffenbuttel1, Anneke C Muller Kobold3
1Department of Endocrinology, University of Groningen, University Medical Center Groningen, The Netherlands.
Endocrine connections
|October 19, 2023
概括
甲状腺激素 (TH) 用户经历更多的并发症,这进一步降低了他们的健康相关的生活质量 (HRQoL) 添加方式,突出结合条件的影响.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 生活质量研究 研究 生命质量研究
背景情况:
- 用甲状腺激素 (TH) 治疗治疗的甲状腺功能低下症与与健康相关的生活质量 (HRQoL) 的降低有关.
- 甲状腺功能低下症和并发性疾病对HRQoL的潜在协同效应需要进一步调查.
研究的目的:
- 调查使用TH的个体中并发性疾病的患病率.
- 确定TH使用和并发症对HRQoL的影响.
- 检查TH使用和并发症对HRQoL的综合影响.
主要方法:
- 对基于人口的生命线队列数据的分析 (N=14,720).
- 通过问卷,体检,生化测量和药物审查来评估并发症,分为14个疾病领域.
- 使用RAND-36测量HRQoL,使用后勤回归进行统计分析.
主要成果:
- 甲状腺激素 (TH) 用户 (4537/14,720) 的共发病率较高,其中85%的患者至少有一种受影响的疾病领域,而非使用者中有71%的患者.
- 使用TH与14个疾病领域中的13个疾病领域的可能性增加以及八个维度中的六个维度中的HRQoL降低有关.
- 在TH使用和受影响的疾病领域之间没有发现显著的相互作用;并发症增加了对TH使用者的HRQoL的负面影响.
结论:
- 使用甲状腺激素 (TH) 的人具有明显更高的并发性疾病负担.
- 伴随性疾病的存在加剧了TH使用对健康相关生活质量 (HRQoL) 的负面影响.
- 管理并发性疾病对于改善甲状腺功能低下症患者的HRQoL至关重要.
相关概念视频
Factors Affecting Illness
4.2K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
4.2K
Synthesis and Regulation of Thyroid Hormones
4.7K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.7K
Lifestyle Factors and Health
62
Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
62
Functions of Thyroid Hormones
2.8K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.8K
Hypertension III: Clinical Manifestations and Diagnostic Studies
15
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
15
Dimensions of Health and Illness
7.4K
The factors influencing the health-illness continuum can be internal or external and may or may not be under conscious control. They are related to the following eight human dimensions, and each dimension is interrelated to one other.
7.4K

