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Generation of Escape Variants of Neutralizing Influenza Virus Monoclonal Antibodies
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人类抗体对Omicron亚系的广泛中和和XBB变异的逃避的结构基础

Hui Sun1, Yizhen Wang1, Xiuting Chen1

  • 1State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, School of Life Sciences, Xiamen University , Xiamen, China.

Journal of virology
|October 19, 2023
PubMed
概括

像Omicron XBB这样的新型SARS-CoV-2变种逃避中和抗体,降低了疫苗的有效性. 这项研究结构性地解释了如何通过这些新兴变体绕过3类中和抗体.

关键词:
这就是SARS-CoV-2病毒.广泛的中和,广泛的中和.低温电磁波冷却器 (Cryo-EM) 是一个非常好的方法.免疫逃避 免疫逃避中和抗体的抗体中和.

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