青少年体重的发育轨迹 青少年面临主要情绪障碍的风险
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Updated: Jul 12, 2025

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Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
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Nitya Adepalli1,2, Jill Cumby2, Niamh Campbell1,2
1Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
JAMA network open
|October 19, 2023
概括
有情绪障碍家族病史的女性在青春期左右开始体重增加. 这发生在情绪障碍发作之前,这表明早期干预对有风险的年轻人至关重要.
科学领域:
- 精神病学是一个精神病学.
- 儿科 儿科 儿科
- 遗传学 是一个遗传学.
背景情况:
- 情绪障碍与体重增加有关,特别是在女性身上.
- 这种体重增加与家族风险相关的发病时间尚不清楚.
研究的目的:
- 为了调查情绪障碍家族风险的年轻人的性别特异性体重轨迹.
- 与对照人群相比,确定风险青少年体重差异开始的年龄.
主要方法:
- 一项基于社区的队列研究跟踪了394个未受影响的后代 (3-20岁) 的父母有或没有情绪障碍,持续了5年.
- 身体质量指数 (BMI) 的z-score被分析使用重复测量回归,考虑到性别和潜在的混因素.
主要成果:
- 总的来说,与对照组相比,家族风险的年轻人体重没有显著差异.
- 处于家族风险的女性从12岁起的BMIz分数显著增加,这表明青春期周围体重增加.
- 具有家族风险的男性在任何年龄段的体重与对照群没有差异.
结论:
- 具有情绪障碍家族史的女性倾向于从青春期开始体重增加.
- 这种体重增加先于情绪障碍的出现,突出了早期干预的关键窗口.
- 干预措施应从童年开始,以减轻这一脆弱人群的不良心理和身体健康结果.
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