ART2Dose:在线适应性放射治疗的综合剂量验证平台
Jingying Lin1, Mingli Chen1, Youfang Lai1
1Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Medical physics
|October 19, 2023
概括
一个新的软件,ART2Dose,简化了在线适应性放射治疗 (ART) 的质量保证. 它提供了高效和准确的剂量验证,减少了治疗检查时间,并改善了圆束CT和MRI导向ART的临床工作流程.
科学领域:
- 医学物理 医学物理
- 辐射瘤学 辐射瘤学
- 放射治疗技术 放射治疗技术
背景情况:
- 在线适应性放射治疗 (ART) 需要快速,准确的剂量验证.
- 目前商业软件的局限性阻碍了在时间敏感的在线ART工作流程中高效的二次剂量检查.
- 对体积剂量分配的独立验证对于适应性计划的准确性至关重要.
研究的目的:
- 推出ART2Dose,这是一个高效的在线质量保证 (QA) 平台,用于在线ART.
- 评估ART2Dose在Ethos和Unity治疗输送系统上的表现.
- 评估平台与临床质量保证工作流程的整合.
主要方法:
- 开发了ART2Dose,这是一个具有集成工作流程 (数据库,计算服务器,报告生成器,网页门户) 的二次剂量验证软件.
- 在40个适应性计划的临床前评估中,ART2剂量与Mobius3D进行了比较.
- 对1302个形光束CT导向自适应放射治疗 (CTgART) 和1278个MR图像导向自适应放射治疗 (MRgART) 分数进行了回顾性分析.
主要成果:
- ART2Dose显示了与Mobius3D.相比的或更高的马传导率.
- 治疗前检查时间减少了每计划3-4分钟.
- 追溯分析显示,CTgART的平均马通过率为99.61%,MRgART的平均通过率为97.75%.
- 平均计算时间为CTgART约1分钟,MRgART约2分钟.
结论:
- 通过简化实施,ART2Dose显著提高了在线ART工作流程.
- 该平台提供可靠和高效的在线质量保证,减少临床时间压力.
- ART2Dose将劳动密集型任务降至最低,提高了适应性放射治疗的整体效率.
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