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系统Xc-在口腔状细胞癌的葡萄糖枯竭下加剧了代谢压力

Miao Wang1,2, Bo Li1, Wanrong Meng1,2

  • 1State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.

Oral diseases
|October 19, 2023
PubMed
概括

葡萄糖耗尽会通过Xc系统 (一种谷氨酸/氨酸反载体) 触发口腔状细胞癌 (OSCC) 中的细胞死亡. 这一发现支持葡萄糖饥饿疗法作为OSCC的治疗策略.

关键词:
铁性化 (ferroptosis) 是一种葡萄糖的饥饿 葡萄糖的饥饿谷氨胺/谷氨酸酸的阿纳普勒罗斯症系统Xc− 系统瘤代谢 瘤代谢

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