螺旋细胞占主导地位的三旋盘瘤与化安排:一种罕见的变体
Anthony Linfante1, Brenda Carrillo2, Jason Jones3
1Department of Dermatology and Dermatopathology, University of Texas Medical Branch, Galveston, TX.
The American Journal of dermatopathology
|October 19, 2023
概括
螺旋细胞占主导地位的三角瘤 (SCPT) 是一种良性皮肤瘤. 鉴定出一种罕见的SCPT形变体,它可能模仿s schwannoma,但通过特定的免疫组织化学标记来区分.
科学领域:
- 皮肤病理学 皮肤病理学
- 在瘤学瘤学.
背景情况:
- 螺旋细胞占主导地位的三角瘤 (SCPT) 是一种良性瘤,属于三角瘤-纤维瘤谱.
- SCPT通常呈现为面部斑块,并以细胞状细胞增殖为特征.
研究的目的:
- 报告一种罕见的SCPT变体,其表现为状的螺旋细胞排列.
- 为了区分这种变体与类似的新生瘤,如 schwannoma.
主要方法:
- 皮肤活检的组织病理学检查来自患有鼻的患者.
- 使用CD34,S100和SOX10标记物的免疫组织化学分析.
主要成果:
- 病变显示了纤维肌状肌层和外周脂质腺增生症内的平淡的状细胞在化的模式中.
- 免疫组织化学检查显示,CD34表达强,S100和SOX10染色负.
- 杆状的图案类似于在斯万诺玛看到的Verocay身体.
结论:
- 具有形图案的SCPT是一种罕见的组织病理变异.
- 这种变异可以通过其上皮组成部分和独特的免疫组织化学特征 (CD34+,S100-,SOX10-) 来区分出斯万诺马.
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