在患有甲状腺相关眼病症的患者中,胸膜厚度,通过扫描源光学连贯性断层扫描来确定
Sisi Zhong1,2, Fanglin He1,2, Sijie Fang1,2,3,4
1Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
The British journal of ophthalmology
|October 19, 2023
概括
在活跃的甲状腺相关眼科医症 (TAO) 中,subfoveal冠状腺厚度 (SFCT) 显著增加. 扫描源光学连贯性断层扫描 (SS-OCT) 可以非侵入性地评估这种变化,用于疾病监测.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 医疗成像医学成像
背景情况:
- 甲状腺相关眼病 (TAO) 是一种影响眼睛的自身免疫性疾病.
- 评估TAO活动和严重程度对于有效管理至关重要.
- 底状厚度 (subfoveal choroidal thickness,SFCT) 是一种潜在的眼球炎症指标.
研究的目的:
- 在患有甲状腺相关眼病症 (TAO) 的患者中调查亚叶胆道厚度 (SFCT).
- 通过扫描源光学连贯断层扫描 (SS-OCT) 将SFCT与疾病活性和严重程度相关联.
主要方法:
- 招募了30名TAO患者和38名健康对照.
- 使用标准化标准对疾病活动和严重程度进行了分级.
- 使用扫描源光学连贯性断层扫描 (SS-OCT) 来测量SFCT.
主要成果:
- 与非活性TAO和健康对照相比,活跃TAO患者的平均SFCT显著更厚.
- SFCT的变化显示出在区分活性和非活性TAO (AUC=0.659) 中的预测能力.
- 在中度至重度/重度的TAO和健康对照之间没有发现SFCT显著差异.
结论:
- SFCT与TAO的临床活动得分密切相关.
- 在活跃的TAO中显而易见的胆道结.
- SS-OCT提供了一种非侵入性的方法来监测TAO的进展和治疗反应.
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