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Updated: Jul 12, 2025

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
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在可卡因依赖中的血内分类素及其与大脑甲基胺酸受体5密度的关系

Sara L Kroll1, Lea M Hulka2, Ann-Kathrin Kexel2

  • 1Experimental and Clinical Pharmacopsychology, Department of Psychiatry, Psychotherapy, and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland. saraliane.kroll@bli.uzh.ch.

Translational psychiatry
|October 19, 2023
PubMed
概括

这项研究在依赖可卡因的使用者中发现了更高的2 - 阿拉基多诺伊尔甘油醇 (2 - AG) 水平,将外围的2 - AG与大脑甲基胺-5受体 (mGluR5) 密度联系起来. 这些发现表明,内分泌大麻素系统 (ECS) 是可卡因依赖的潜在治疗点.

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