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Updated: Jul 12, 2025

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
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Published on: November 3, 2010

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发现对基因表达和复杂特征的遗传影响的系统差异

Hakhamanesh Mostafavi1, Jeffrey P Spence2, Sahin Naqvi2,3

  • 1Department of Genetics, Stanford University, Stanford, CA, USA. hmostafavi@stanford.edu.

Nature genetics
|October 19, 2023
PubMed
概括

全基因组关联研究 (GWAS) 和表达量化特征位点 (eQTLs) 识别了不同的遗传变异. 接近GWAS的基因具有复杂的调节,并且正在选择中,与接近eQTL的基因不同,这表明需要补充功能方法.

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