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Updated: Jul 12, 2025

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在Drosophila melanogaster中piRNA集群的组成偏离了陷模型下的预期

Filip Wierzbicki1,2, Robert Kofler3

  • 1Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria.

BMC biology
|October 20, 2023
PubMed
概括

在动物中对可移植元素 (TE) 控制的广泛接受的"陷模型"受到挑战. 我们对Drosophila melanogaster的种群遗传学研究表明,piRNA集群不作为简单的转子子陷而起作用.

关键词:
这种植物是Drosophila melanogaster.基因组的演变 基因组的演变人口遗传学 人口遗传学可转移的要素是可以转移的.陷模型 陷模型在piRNA群集中.

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PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs while only 2000 genes have been found for miRNAs. piRNAs can act at the transcriptional and post-transcriptional levels and have a vital role in silencing transposable elements present in germ cells. They are also involved in epigenetic silencing and activation. Previously, they were thought to function only in germ cells but new evidence suggests...
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