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分析2016年北克局部性前列腺癌的积极监测吸收率:加拿大双中心研究和与2010年数据的比较

C Dariane¹, F Chierigo², V Ouellet³

¹Institut du cancer de Montréal, centre de recherche du centre hospitalier de l'université de Montréal (CRCHUM), Montréal, Canada; Department of Urology, hôpital européen Georges-Pompidou, Paris University, 20, rue Leblanc, 75015 Paris, France.

The French journal of urology

|October 20, 2023

概括

针对低风险前列腺癌 (PC) 的积极监测 (AS) 越来越多地被采用,特别是在社区中心. 虽然最初的坚持率很高,但长期的维护需要改进.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
在瘤学瘤学.
公共卫生公共卫生

背景情况:

积极监测 (AS) 是管理低风险前列腺癌 (PC) 的关键策略.
评估北克的AS普及率提供了加拿大当前的数据.
与2010年数据的比较凸显了PC管理的趋势.

研究的目的:

评估2016年北克省AS的采用率.
将当前的AS使用与2010年加拿大历史数据进行比较.
在诊断后6个月和12个月评估AS的坚持.

主要方法:

2016年对259名患有局部性结核病的男性进行了回顾性图表审查.
纳入标准:NCCN低风险 (LR) -PC,包括非常低风险 (VLR) 和有利的中间风险 (FIR) -PC.
被定义为在6个月内没有激进治疗的初始策略.

主要成果:

50.2%的患者患有非常低风险PC (VLR-PC).
六个月的AS遵守率为LR-PC的81%和FIR-PC的65%.
12个月的AS维护率下降到69% (LR-PC) 和58% (FIR-PC);VLR-PC启动率为98%,下降到12个月的85%.

结论:

大多数低风险前列腺癌患者在2016年开始AS.
与2010年相比,VLR-PC患者的AS发病率较高.
鼓励AS至关重要,重点是改善12个月的维护和长期结果.

关键词:

积极监视活动的积极监视.加拿大前列腺癌生物标志物网络.前列腺癌是什么意思前列腺癌是什么意思

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