在炎症性肠道疾病的第三级转诊中心的监测计划下检测失育症的发病率:现实世界的数据
Yifat Snir1, Jacob E Ollech1, Noam Peleg1
1IBD Center, Division of Gastroenterology, Rabin Medical Center, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
高风险的炎症性肠病 (IBD) 患者可以从监测结肠镜中获益. 一个专门的程序实现了高的发育不良检测率 (DDR),这表明DDR应该成为IBD监测的标准化质量衡量标准.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 内镜检查是指内镜检查.
背景情况:
- 监测结肠镜对于高风险炎症性肠病 (IBD) 患者来说至关重要,以检测结肠直肠癌 (CRC).
- 目前,在IBD监测中没有确立的成形障碍检测率 (DDR) 的质量指标.
- 这项研究在专门的IBD监测计划中评估了DDR.
研究的目的:
- 在专门的IBD监测计划中评估生殖不良的检测率 (DDR).
- 为了确定与发育不良检测相关的风险因素.
- 建议DDR作为IBD监测的质量指标.
主要方法:
- 一项横截面研究招募了119名患有静止性结肠炎的患者,这些患者接受了用染色色体内镜 (DCE) 进行高清结肠镜检查.
- 晚期发育不良 (AD) 被定义为低度发育不良≥10毫米,高度发育不良或结直肠癌.
- 分析了发育不良检测的危险因素.
主要成果:
- 在151项手术中,发现了206个病变,其中40个是发育不良和7个是晚期发育不良 (AD).
- 每次损伤和每次手术的DDR分别为19.4%和20.5%,每次手术的ADDR为4.6%.
- 库多坑模式II-V显示出高灵敏度 (92.5%),但对于发育不良的检测,错误阳性率高 (64.8%). 年龄和有史以来的发育不良与检测有关.
结论:
- 一个专门的监控程序在现实环境中实现了高DDR.
- 该研究建议定义和实施最佳的DDR作为IBD监测计划的标准化质量衡量标准.
- 这旨在改善高风险IBD患者的结直肠癌检测.
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