一个右可以做一个左:在围产中风后右半球的句子处理
Kelly C Martin1, Anna Seydell-Greenwald1,2, Peter E Turkeltaub1,2
1Center for Brain Plasticity and Recovery, Georgetown University Medical Center, Georgetown University, Washington, DC 20057, United States.
Cerebral cortex (New York, N.Y. : 1991)
|October 20, 2023
概括
患有左半球中风的儿童表现出右半球大脑对语言的可塑性. 右半球招募的区域反映了典型的左半球语言区域,使得成功的语言发展.
科学领域:
- 神经科学是一个神经科学.
- 发育神经科学的发展神经科学.
- 认知神经科学 认知神经科学
背景情况:
- 围产期中风可能会损害成人认知功能的关键大脑区域.
- 了解大脑可塑性对于预测早期脑损伤后的功能结果至关重要.
研究的目的:
- 调查影响左半球 (LH) 的围产中风后右半球 (RH) 的语言组织.
- 确定左半球周产中风 (LHPS) 患者的RH语言招募是否反映了典型的LH组织.
主要方法:
- 在听觉句子理解任务期间,分析了14名LHPS参与者和11名健康对照者的fMRI数据.
- 采用"顶级voxel"方法来标准化对半球和参与者之间活跃大脑voxel的比较.
- 在LHPS参与者和对照者的半球之间比较了功能性大脑组织.
主要成果:
- LHPS参与者一直在招募RH区域,这些区域反映了典型的LH语言区域.
- 在LHPS参与者中激活的RH区域与典型的LH区域比典型的RH区域更好地对齐.
- 在RH的招募模式与强烈激活的LH控制区域更相似.
结论:
- 在LH周产中风后,RH的成功语言发展可能涉及招募前部区域的特定安排.
- 这种RH安排似乎反映了典型的主导LH语言网络组织.
- 研究结果表明,尽管早期出现脑损伤,语言的神经组织的模式仍然存在.
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