药剂师主导的抗菌管理和抗生素在COVID-19住院患者的使用
Selena N Pham1, Taylor M Hori1, Ashfaq Shafiq1
1Veterans Affairs Southern Nevada Healthcare System, Las Vegas.
在住院的COVID-19患者中,有31%接受了抗生素治疗,但在许多情况下,药剂师领导的抗菌管理计划 (ASP) 提前停止了这些治疗. 在对COVID-19患者进行实证抗生素治疗之前,对细菌共感染的仔细评估至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- COVID-19大流行导致住院患者的经验性抗生素使用增加.
- 抗菌药物管理计划 (ASP) 旨在改善抗生素处方.
- ASP药剂师可以修改抗感染疗法.
研究的目的:
- 描述退伍军人事务机构对COVID-19患者的抗生素处方模式.
- 评估药剂师领导的ASP的影响.
- 在这个队列中确定细菌共感染的流行率.
主要方法:
- 对2020年11月1日至2021年1月31日期间入院的COVID-19患者的回顾性图表审查.
- 由ASP团队对抗生素启动和停止的分析.
- 鉴定微生物学证实的细菌共感染.
主要成果:
- 在199名COVID-19患者中,31%的患者在入院时接受了抗生素.
- 77%的抗生素疗程在72小时内被ASP中止.
- 在3%的患者中确认了细菌共感染;8%的患者患上了医院感染.
结论:
- 在COVID-19患者怀疑的细菌共感染时,实证抗生素的使用在多达31%的病例中被观察到.
- 药剂师主导的ASP有效地促进了早期停止使用抗生素.
- 在实证抗生素使用之前,对细菌共感染的临床评估至关重要,以对抗抗菌素耐药性.
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