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一个线粒体检查点适应性抗癌免疫

Oliver Kepp1,2,3, Peng Liu1,2, Guido Kroemer1,2,4

  • 1Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM U1138, Institut Universitaire de France, Paris, France.

Oncoimmunology
|October 20, 2023
PubMed
概括

该BCL2蛋白保持线粒体的完整性,抑制先天免疫和亡. 新的数据显示,BCL2也抑制了树突细胞的适应性免疫力,这表明它具有广泛的免疫抑制作用.

关键词:
抗原呈现方式在CGAS中,CGAS是最重要的.免疫检查点抑制剂 免疫检查点抑制剂免疫性细胞死亡 免疫性细胞死亡我们的mtDNA mtDNA这是一种I型干扰子.

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