科威特的万科米辛和线索利德的有效性,安全性和成本:一项回顾性队列研究
Sarah S Alghanem1, Moetaza M Soliman2, Sarah Al-Manie1
1Department of Pharmacy Practice, College of Pharmacy, Kuwait University, Safat 13110 Kuwait.
概括
在科威特,万科米辛,提科普拉宁和莱因佐利德在治疗格拉姆阳性感染方面是有效的,具有相似的安全性. 利尼佐利德和万科米辛的治疗成本很高,这凸显了需要具有成本效益的抗生素策略的需要.
科学领域:
- 药理学 药理学是指药理学的学科.
- 传染性疾病 传染性疾病
- 卫生经济学 卫生经济学
背景情况:
- 此前,在科威特治疗格拉姆阳性细菌感染的万科米辛和线索利德的有效性,安全性和成本是未知的.
- 这项研究的目的是评估这些关键方面,万科米辛,提科普拉宁,和linezolid在科威特医疗保健环境.
研究的目的:
- 评估万科米辛,提科普拉宁和线索利德在治疗阳性细菌感染中的临床有效性.
- 评估与这些抗生素相关的安全性概况和不良事件发生率.
- 分析与住院患者使用这些抗生素相关的直接医疗成本.
主要方法:
- 在五家科威特医院进行了一项回顾性研究,涉及成年患者,这些患者被处方为万科米辛,提科普拉宁或线索利德治疗阳性感染.
- 使用描述性统计数据来分析有效性和安全性结果.
- 一个全面的成本分析专注于住院患者.
主要成果:
- 在116名患者中,49名患者接受了糖 (万科米辛或提科普拉宁),67名患者接受了linezolid.
- 临床治愈率很高 (100名患者),抗生素组之间没有显著差异 (p=0.34).
- 所有药物中,血小板缺血和急性损伤的发生率相似,没有统计学上显著的差异.
结论:
- 糖和线化物在治疗阳性感染方面表现出高效.
- 最常被处方的线索利德 (Linezolid) 的有效性和安全性与其他药物相比相当.
- 用线索利德和万科米治疗与大量医疗费用有关,这表明在选择抗生素时需要考虑经济因素.
关键词:
费用 费用 费用 费用 费用 费用 费用线索化物 线索化物甲素耐药的金黄色葡萄球菌 (Staphylococcus aureus) 是一种泰科普拉宁是一种血小板缺血症 血小板缺血症范科米辛是一种药物.更多相关视频
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