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Updated: Jul 12, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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转录因子IRF4决定了CD8+T细胞的抗瘤免疫力

Hui Yan1,2, Yulin Dai3, Xiaolong Zhang1

  • 1Immunobiology & Transplant Science Center, Department of Surgery, Houston Methodist Research Institute & Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX 77030, USA.

iScience
|October 20, 2023
PubMed
概括

干扰素调节因子4 (IRF4) 对于T细胞透和瘤中的功能至关重要. 工程IRF4增强了抗瘤免疫力和T细胞疗效,提供了一个有前途的癌症免疫治疗策略.

关键词:
癌症 癌症 癌症 癌症细胞生物学 细胞生物学免疫学 免疫学 免疫学分子生物学分子生物学

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