人工智能在神经退行性疾病管理中的作用
Sanchit Dhankhar1,2, Somdutt Mujwar1, Nitika Garg1,2
1Chitkara College of Pharmacy, Chitkara University, Punjab, India.
CNS & neurological disorders drug targets
|October 20, 2023
概括
人工智能和机器学习等计算方法为检测和治疗神经退行性疾病提供了新的途径. 这些先进的方法有助于了解疾病机制和个性化患者护理,以获得更好的结果.
科学领域:
- 计算神经科学是一种神经科学.
- 神经退行性疾病研究研究
- 人工智能在医学中的应用
背景情况:
- 神经退行性疾病涉及不可逆转的神经功能损失,需要有效的检测和治疗,以提高患者的生活质量.
- 计算机技术的进步使得管理和治疗这些复杂疾病的新策略成为可能.
研究的目的:
- 探索计算方法的应用,包括药物设计,人工智能 (AI),机器学习 (ML) 和深度学习 (DL),用于神经退行性疾病的治疗.
- 审查早期检测计算方法的潜力,量化疾病进展,并了解潜在的生物机制.
- 讨论挑战,未来的方向,以及针对神经退行性疾病护理的个性化计算模型的开发.
主要方法:
- 关于用于神经退行性疾病的计算方法的当前文献的综述.
- 对AI,ML和DL技术进行疾病检测,进展监测和机制阐明的分析.
- 探索针对个性化治疗策略的计算建模.
主要成果:
- 计算方法在早期诊断和跟踪神经退行性疾病进展方面显著有前途.
- 人工智能,ML和DL可以增强对驱动这些疾病的复杂生物机制的理解.
- 开发个性化的计算模型可以为个别患者量身定制护理.
结论:
- 计算方法为推进神经退行性疾病研究和临床实践提供了强大的工具.
- 未来的研究应该专注于克服挑战,并整合这些技术,以改善患者的治疗结果.
- 突出计算技术的优缺点对于其有效的临床转化至关重要.
相关概念视频
Alzheimer's Disease: Treatment
200
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
200
Alzheimer's Disease: Overview
500
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
500
Parkinson's Disease: Overview
567
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
567
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
131
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
131
Neural Regulation
39.5K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.5K
Parkinson's Disease: Treatment
281
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
281


