治疗儿童维生素D缺乏症的方法
Philip R Fischer1,2,3, Casey R Johnson4, Kaitlin N Leopold1
1Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN USA.
Expert review of endocrinology & metabolism
|October 20, 2023
概括
维生素D缺乏在儿童中很常见,导致严重的健康问题,如风和低血症. 早期诊断和治疗对于预防长期的代谢和神经系统问题至关重要.
科学领域:
- 儿科 儿科 儿科
- 内分泌学 在内分泌学.
- 营养科学 营养科学
背景情况:
- 维生素D缺乏影响10-50%的儿科人口.
- 它会导致婴儿和儿童患风和低血症等严重疾病.
- 缺乏症增加了成人代谢和神经系统疾病的风险.
研究的目的:
- 审查儿童维生素D缺乏症的诊断,预防和治疗.
- 强调需要进一步研究长期影响和查.
主要方法:
- 自1940年以来,PubMed的综合文献搜索.
- 包括来自审查文献的参考文献.
- 分析诊断标准,临床特征和治疗方案.
主要成果:
- 诊断依赖于血清25-基维生素D水平;病呈现骨变形和性酸酶升高.
- 许多维生素D缺乏的儿童无症状.
- 预防策略包括阳光照射,食品强化和补充.
- 治疗包括口服或注射维生素D,剂量建议各不相同.
结论:
- 进一步的研究是必要的,以了解儿童维生素D缺乏的非骨影响.
- 需要研究补充剂对无症状个体的益处.
- 建议为无症状儿童和青少年制定适当的查指南.
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