性别作为急性损伤的一个生物变量
Anita Dahiya1, Neesh Pannu1, Danielle E Soranno2,3
1Division of Nephrology, University of Alberta, Department of Medicine, Alberta, Canada.
Current opinion in critical care
|October 20, 2023
概括
性别和性别显著影响急性损伤 (AKI) 的发展和结果. 了解这些差异对于改善患者护理和AKI的研究可重复性至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 翻译医学是一种翻译医学.
- 医学中的性别和性别.
背景情况:
- 性别是急性损伤 (AKI) 研究中的关键生物变量,影响疾病的发展和进展.
- 虽然动物模型显示了AKI后心脏结局的明显性别差异,但人类AKI发病率的数据是矛盾的,最近的研究表明男性的发病率更高.
- 妇女在AKI后经常经历更糟糕的结局,性别可能会影响寻求医疗保健的行为和治疗策略.
结论:
- 承认性别是生物变量对于推进AKI研究和提高科学严谨性至关重要.
- 调查性别差异对于优化AKI临床管理和患者结果至关重要.
- 未来的翻译研究必须纳入性别和性别方面的考虑,以提高可复制性和临床相关性.
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